Cambridge Healthtech Institute’s fifth annual conference on Predicting Drug-Induced Cardiotoxicity will cover- • Early Assessments- Assays, In Vitro and In Vivo Models and Biomarkers for Detecting and Monitoring Cardiotoxicity Early in the Pre-clinical S

World Pharma Congress 2012 encompasses a broad spectrum of topics that are very important and relevant to scientists in academia as well as those in the pharmaceutical and biotechnology industry.

Cambridge Healthtech Institute’s fourth annual conference on Tackling Drug-Induced Idiosyncratic Hepatotoxicity focuses on: • Strategies for tackling Idiosyncratic Drug-Induced Liver Injury (IDILI) • In silico tools for predicting hepatotoxicity • New

This DVD covers the progression of “creating a best of breed informatics organization” from the basics of biology and genetics to application of semantic technologies. Through modeling, case studies, and best practice examples, participants will learn techniques on how to combine data in a meaningful way.

Since its market introduction circa 30 years back, dynamic light scattering (DLS) has occupied a position of increasing popularity within the area of protein aggregate detection and characterization, due in large part to the non-invasiveness of the technique, the minimal sample volume & concentration requirements, and the quickness of data collection. While modern instrument design and software have removed much of the mystic traditionally associated with the technique, data interpretation is still an area of frustration for many DLS users. This workshop covers the basic theory behind DLS instrumentation, with a focus on the do's & don'ts when it comes to data interpretation.

Sub-visible particles present in these products are a product quality attribute and a potential patient safety concern yet to be fully explored. Early and consistent particle detection, quantitation and control throughout the product life cycle of these drugs from development to commercial lot release is critical in mitigating any concerns. This requires appropriate analytical methods which can be applied to biopharmaceuticals across a large variety of protein concentrations and modes of administration. This workshop and interactive discussion will cover strategies to utilize complementary methods and techniques at different phases of product development.